H2-O influence on antigen presentation in H2-E-expressing mice
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چکیده
منابع مشابه
H2-EB1 Molecule Alleviates Allergic Rhinitis Symptoms of H2-Eb1 Knockout Mice
Background: H2-EB1 molecule which is the homolog of Human HLA-DRB1 is proposed to be associated with allergic rhinitis (AR). Construction of H2-Eb1 knockout animal models provides a tool to elucidate the role of H2-EB1 and AR pathogenesis. Objective: To establish the H2-Eb1 knockout model and investigate the H2-EB1 functions in H2-Eb1 knockout mice as a model of AR. Methods: The Cre/Lox...
متن کاملAbove threshold photodissociation in H2 and H2+
A coupled equations approach is used to calculate the probabilities of photophysical processes in the ten photon absorption spectrum of H2 at wavelength A = 532nm At high intensities, ie, I~10~°W/cm~, it is shown that above threshold photodissocianon (ATPD) occurs readily m the B ~3]
متن کاملH2-O inhibits presentation of bacterial superantigens, but not endogenous self antigens.
H2-O/HLA-DO are MHC class II accessory molecules that modulate exogenous Ag presentation. Most class II accessory molecules are expressed in all professional APC; however, H2-O is only expressed in B cells and medullary thymic epithelial cells. Because B cells present exogenous Ags and superantigens (SAgs), and medullary thymic epithelial cells are specialized APC for self Ags during negative s...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2003
ISSN: 0014-2980,1521-4141
DOI: 10.1002/eji.200323853